{"id":61602,"date":"2026-05-22T13:07:36","date_gmt":"2026-05-22T10:07:36","guid":{"rendered":"https:\/\/ayyildizgundem.net\/?p=61602"},"modified":"2026-05-22T13:07:36","modified_gmt":"2026-05-22T10:07:36","slug":"tubitak-destekli-proje","status":"publish","type":"post","link":"https:\/\/ayyildizgundem.net\/index.php\/2026\/05\/22\/tubitak-destekli-proje\/","title":{"rendered":"T\u00dcB\u0130TAK DESTEKL\u0130 PROJE"},"content":{"rendered":"

Mu\u011fla S\u0131tk\u0131 Ko\u00e7man \u00dcniversitesinde (MSK\u00dc) bilim insanlar\u0131nca 3 y\u0131ld\u0131r y\u00fcr\u00fct\u00fclen bir projeyle, iki farkl\u0131 denizanas\u0131 ve bir anemon t\u00fcr\u00fcnden elde edilen zehrin kolon kanseri h\u00fccreleri \u00fczerindeki olumlu etkileri tespit edildi.<\/p>\n

\"\"<\/p>\n

MSK\u00dc Su \u00dcr\u00fcnleri Fak\u00fcltesi ile T\u0131p Fak\u00fcltesinin ortak y\u00fcr\u00fctt\u00fc\u011f\u00fc projede, iki farkl\u0131 denizanas\u0131 ve bir anemon t\u00fcr\u00fcnden elde edilen venomlar\u0131n (zehir) kolon kanseri h\u00fccreleri \u00fczerindeki etkileri ile venomlar\u0131n sa\u011fl\u0131kl\u0131 ba\u011f\u0131rsak h\u00fccreleri \u00fczerindeki etkileri de incelendi. Proje y\u00fcr\u00fct\u00fcc\u00fcs\u00fc Su \u00dcr\u00fcnleri Fak\u00fcltesi Deniz Biyolojisi Ana Bilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Do\u00e7. Dr. Nur\u00e7in Killi ile T\u0131p Fak\u00fcltesi T\u0131bbi Biyoloji Ana Bilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Do\u00e7. Dr. Esin Sakall\u0131 \u00c7etin ve y\u00fcksek lisans, doktora \u00f6\u011frencilerinin katk\u0131s\u0131yla ger\u00e7ekle\u015ftirilen ara\u015ft\u0131rma, bir kanser t\u00fcr\u00fcn\u00fcn iki farkl\u0131 h\u00fccre hatt\u0131nda ve \u00fc\u00e7 farkl\u0131 deniz canl\u0131s\u0131 zehriyle yap\u0131lan d\u00fcnyadaki ilk \u00e7al\u0131\u015fma olma \u00f6zelli\u011fi ta\u015f\u0131yor.<\/p>\n

Do\u00e7. Dr. Nur\u00e7in Killi, denizanalar\u0131 ve anemon zehirlerinin kolon kanseri h\u00fccrelerindeki etkisi \u00fczerine 2023 y\u0131l\u0131nda T\u00dcB\u0130TAK deste\u011fiyle bir proje ba\u015flatt\u0131klar\u0131n\u0131 s\u00f6yledi. Projenin, Do\u00e7. Dr. Esin Sakall\u0131 \u00c7etin ve \u00f6\u011frencilerle birlikte y\u00fcr\u00fct\u00fcld\u00fc\u011f\u00fcn\u00fc belirten Killi, ara\u015ft\u0131rman\u0131n sonu\u00e7lar\u0131n\u0131n umut verici oldu\u011funu ifade etti. \u00c7al\u0131\u015fma kapsam\u0131nda iki farkl\u0131 denizanas\u0131 t\u00fcr\u00fc ile bir anemon t\u00fcr\u00fcn\u00fcn venomlar\u0131 (zehirleri), iki ayr\u0131 kolon kanseri h\u00fccre hatt\u0131 \u00fczerinde test edildi\u011fini belirten Killi, “Ara\u015ft\u0131rma sonucunda, denizanas\u0131 ve anemon venomlar\u0131n\u0131n kanser h\u00fccreleri \u00fczerinde \u00f6ld\u00fcr\u00fcc\u00fc etki g\u00f6sterdi\u011fi tespit edildi. Ayn\u0131 zamanda sa\u011fl\u0131kl\u0131 kolon h\u00fccrelerinde ise bu etkinin olduk\u00e7a d\u00fc\u015f\u00fck seviyede kald\u0131\u011f\u0131 belirlendi” dedi.<\/p>\n

Elde edilen sonu\u00e7lar\u0131n bilimsel a\u00e7\u0131dan olduk\u00e7a \u00f6nemli ve istenen nitelikte oldu\u011funu vurgulayan Killi, \u00e7al\u0131\u015fman\u0131n d\u00fcnyada ilk kez iki farkl\u0131 kolon kanseri h\u00fccre hatt\u0131nda \u00fc\u00e7 farkl\u0131 t\u00fcr\u00fcn venomlar\u0131n\u0131n birlikte incelendi\u011fi ara\u015ft\u0131rma olma \u00f6zelli\u011fi ta\u015f\u0131d\u0131\u011f\u0131n\u0131 s\u00f6yledi. Ara\u015ft\u0131rman\u0131n \u00f6zg\u00fcn y\u00f6nlerinden birinin ise “g\u00f6\u00e7men denizanas\u0131” olarak bilinen Rhopilema nomadica t\u00fcr\u00fc \u00fczerine yap\u0131lan \u00e7al\u0131\u015fma oldu\u011funu ifade eden Killi, bu t\u00fcr\u00fcn S\u00fcvey\u015f Kanal\u0131 \u00fczerinden Akdeniz\u2019e giri\u015f yapt\u0131\u011f\u0131n\u0131 belirtti.<\/p>\n

T\u00fcrkiye sular\u0131nda yay\u0131l\u0131m g\u00f6steren bu t\u00fcr\u00fcn, \u00fclkedeki en zehirli ikinci denizanas\u0131 olarak \u00f6ne \u00e7\u0131kt\u0131\u011f\u0131n\u0131 kaydeden Killi, bu canl\u0131ya ait venomun kolon kanseri h\u00fccreleri \u00fczerindeki \u00f6ld\u00fcr\u00fcc\u00fc etkisinin ortaya konuldu\u011funu ve ekonomik de\u011feri olmayan ve insanlara temas etti\u011finde \u015fiddetli yak\u0131c\u0131 olan bu canl\u0131n\u0131n farkl\u0131 kullan\u0131m alanlar\u0131 a\u00e7\u0131s\u0131ndan da \u00f6nemli potansiyel ta\u015f\u0131d\u0131\u011f\u0131n\u0131 dile getirdi. Killi, proje sonu\u00e7lar\u0131n\u0131n da d\u00fcnya genelinde kabul g\u00f6ren prestijli bir bilimsel dergide yay\u0131mland\u0131\u011f\u0131n\u0131 ve bundan b\u00fcy\u00fck gurur duyduklar\u0131n\u0131 kaydetti.<\/p>\n

“KANSER \u0130LA\u00c7LARINDAK\u0130 EN B\u00dcY\u00dcK SORUN, \u0130LACIN KANSER H\u00dcCRES\u0130N\u0130 \u00d6LD\u00dcR\u00dcRKEN SA\u011eLIKLI H\u00dcCRELER\u0130 DE YIPRATMASI”<\/strong><\/p>\n

Do\u00e7. Dr. Esin Sakall\u0131 \u00c7etin ise kanser ila\u00e7lar\u0131ndaki en b\u00fcy\u00fck sorunun ilac\u0131n kanser h\u00fccresini \u00f6ld\u00fcr\u00fcrken sa\u011fl\u0131kl\u0131 h\u00fccreleri de y\u0131pratmas\u0131 oldu\u011funu kaydetti. Deniz canl\u0131lar\u0131n\u0131n zehirlerini kanserli h\u00fccrelere uygulad\u0131klar\u0131nda zehrin se\u00e7ici davrand\u0131\u011f\u0131n\u0131 g\u00f6rd\u00fcklerine i\u015faret eden \u00c7etin, “Yani kanserli h\u00fccreleri h\u0131zla yok ederken sa\u011fl\u0131kl\u0131 kolon h\u00fccrelerine minimum d\u00fczeyde zarar verdi. Bu \u00e7al\u0131\u015fmayla ekosisteme ve insana zarar verdi\u011fi d\u00fc\u015f\u00fcn\u00fclen, ekonomik hi\u00e7bir de\u011feri olmayan bu canl\u0131lar\u0131 t\u0131p d\u00fcnyas\u0131 i\u00e7in de\u011ferli bir ham maddeye d\u00f6n\u00fc\u015ft\u00fcrmeyi ama\u00e7lad\u0131k” diye konu\u015ftu.<\/p>\n

\u00c7etin, h\u00fccre biyolojisi d\u00fczeyinde yapt\u0131klar\u0131 analizlerde, zehrin kanser h\u00fccresinin intihar mekanizmas\u0131n\u0131, yani apoptoz dedikleri programl\u0131 h\u00fccre \u00f6l\u00fcm\u00fcn\u00fc tetikledi\u011fini belirlediklerini anlatarak, \u015f\u00f6yle konu\u015ftu: “Bu zehir, kanser h\u00fccrelerinin i\u00e7ine girerek onlar\u0131n enerji santralleri olan mitokondrileri bozuyor, h\u00fccre i\u00e7i stresi art\u0131r\u0131yor ve kanser h\u00fccresine tabiri caizse kendi kendini yok etme emri veriyor. \u00dcstelik bunu yaparken yan\u0131ndaki sa\u011fl\u0131kl\u0131 kom\u015fu h\u00fccrelere dokunmamaya \u00f6zen g\u00f6steriyor. \u00dclkemizin deniz kaynaklar\u0131n\u0131n sadece turizm ve bal\u0131k\u00e7\u0131l\u0131k i\u00e7in de\u011fil, t\u0131p ve eczac\u0131l\u0131k a\u00e7\u0131s\u0131ndan da ne kadar b\u00fcy\u00fck bir hazine oldu\u011funu g\u00f6stermekten gurur duyuyoruz.”<\/p>\n

\u00c7etin, \u00e7al\u0131\u015fmalar\u0131nda kendilerine destek olan ve emek verenlere te\u015fekk\u00fcr etti.<\/p>\n","protected":false},"excerpt":{"rendered":"

Mu\u011fla S\u0131tk\u0131 Ko\u00e7man \u00dcniversitesinde (MSK\u00dc) bilim insanlar\u0131nca 3 y\u0131ld\u0131r y\u00fcr\u00fct\u00fclen bir projeyle, iki farkl\u0131 denizanas\u0131 ve bir anemon t\u00fcr\u00fcnden elde edilen zehrin kolon kanseri h\u00fccreleri \u00fczerindeki olumlu etkileri tespit edildi. MSK\u00dc Su \u00dcr\u00fcnleri Fak\u00fcltesi ile T\u0131p Fak\u00fcltesinin ortak y\u00fcr\u00fctt\u00fc\u011f\u00fc projede, iki farkl\u0131 denizanas\u0131 ve bir anemon t\u00fcr\u00fcnden elde edilen venomlar\u0131n (zehir) kolon kanseri h\u00fccreleri \u00fczerindeki …<\/p>\n","protected":false},"author":1,"featured_media":61603,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[1191,1895,1463,146],"class_list":["post-61602","post","type-post","status-publish","format-standard","has-post-thumbnail","","category-genel","tag-ayyildiz-gundem","tag-bilim","tag-msku","tag-mugla"],"_links":{"self":[{"href":"https:\/\/ayyildizgundem.net\/index.php\/wp-json\/wp\/v2\/posts\/61602","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ayyildizgundem.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ayyildizgundem.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ayyildizgundem.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ayyildizgundem.net\/index.php\/wp-json\/wp\/v2\/comments?post=61602"}],"version-history":[{"count":1,"href":"https:\/\/ayyildizgundem.net\/index.php\/wp-json\/wp\/v2\/posts\/61602\/revisions"}],"predecessor-version":[{"id":61604,"href":"https:\/\/ayyildizgundem.net\/index.php\/wp-json\/wp\/v2\/posts\/61602\/revisions\/61604"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ayyildizgundem.net\/index.php\/wp-json\/wp\/v2\/media\/61603"}],"wp:attachment":[{"href":"https:\/\/ayyildizgundem.net\/index.php\/wp-json\/wp\/v2\/media?parent=61602"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ayyildizgundem.net\/index.php\/wp-json\/wp\/v2\/categories?post=61602"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ayyildizgundem.net\/index.php\/wp-json\/wp\/v2\/tags?post=61602"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}